Search on: CYTOCHROME P 450 CYP2C8 
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Descriptor English:   Cytochrome P-450 CYP2C8 
Descriptor Spanish:   Citocromo P-450 CYP2C8 
Descriptor Portuguese:   Citocromo P-450 CYP2C8 
Synonyms English:   CYP2C8
CYPIIC8
Cytochrome P450 MP-20
Cytochrome P450, Family 2, Subfamily C, Polypeptide 8
S-Mephenytoin 4-Hydroxylase
4-Hydroxylase, S-Mephenytoin
CYP2C8, Cytochrome P-450
Cytochrome P 450 CYP2C8
Cytochrome P450 MP 20
P-450 CYP2C8, Cytochrome
P450 MP-20, Cytochrome
S Mephenytoin 4 Hydroxylase  
Tree Number:   D08.244.453.005.590
D08.244.453.491.368
D08.811.682.690.708.170.010.590
D08.811.682.690.708.170.450.360
D12.776.422.220.453.010.590
D12.776.422.220.453.491.360
Definition English:   A liver microsomal cytochrome P450 hydroxylase that oxidizes a broad spectrum of substrates including STEROIDS, FATTY ACIDS, and XENOBIOTICS. Examples of pharmaceutical substrates for CYP2C8 include; PACLITAXOL; torsemide; and; AMODIAQUINE 
Entry Combination - descr/qualif English:   Cytochrome P-450 CYP2C8/antagonists & inhibitors use Cytochrome P-450 CYP2C8 Inhibitors
 
History Note English:   2015 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   55607 
Unique Identifier:   D065727 

Occurrence in VHL: 		 

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